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Rabbit Anti-Lambda Light Chain antibody ,1mg/ml

别名:
Cas号: 物化性质:
分子式: 熔点:
分子量: 沸点:
EINECS编号: 密度:
MDL号: 储存条件:

英文名称:Rabbit Anti-Lambda Light Chain antibody 
别    名:Ig lambda chain C regions; Bence Jones protein; BJP; Constant region of lambda light chains; IGLC 1; IGLC 2; IGLC 3; IGLC; IGLC1; IGLC2; IGLC3; LAC1_HUMAN; Immunoglobulin lambda constant 1; Mcg marker; Paraprotein; Ig lambda-1 chain C regions. 
研究领域:肿瘤  细胞生物  免疫学  
抗体来源:Rabbit
克隆类型:Polyclonal
交叉反应: (predicted: Human, Mouse, Rat, )
产品应用:WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量:22.5kDa
细胞定位:分泌型蛋白 
性    状:Liquid
浓    度:1mg/ml
免 疫 原:KLH conjugated synthetic peptide derived from human Lambda Light Chain: 41-106/106 
亚    型:IgG
纯化方法:affinity purified by Protein A
缓 冲 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMedPubMed
产品介绍: All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region.
Subcellular Location:
Cytoplasmic
Similarity:
Contains 1 Ig-like (immunoglobulin-like) domain.
SWISS:
P01701
Gene ID:
3535
Database links:
Entrez Gene: 3535 Human
Entrez Gene: 3546 Human
Entrez Gene: 8217 Human
Omim: 147220 Human
SwissProt: P01701 Human
SwissProt: P01842 Human
该抗体特异识别免疫球蛋白λ轻链,可用于鉴定白血病、浆细胞瘤以及某些非霍奇金氏淋巴瘤。这些肿瘤的共同特征是只限于单个轻链的表达,因此轻链Kappa和Lamda可用于良恶性淋巴病变(反应性淋巴细胞增生和淋巴瘤)的辅助性诊断。 
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Rabbit Anti-Lambda Light Chain antibody